Inhibition of CEBPB Attenuates Lupus Nephritis via Regulating Pim-1 Signaling

Figure 5

The knockdown of CEBPB inhibited the activation of NLRP3 inflammasomes in glomerular podocytes. Interference efficiency of CEBPB siRNAs (a). Protein expression of inflammasome-related proteins in podocytes stimulated with LPS and ATP (b, c). The content of IL-1β (d) and IL-6 (e) in the cell supernatant. (CEBPB, CCAAT/enhancer-binding protein β; ATP, adenosine triphosphate; LPS, lipopolysaccharides).

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