Mediators of Inflammation

Research Article

The Association between Helicobacter pylori Seropositivity and Bone Mineral Density in Adults

Table 2

Association of H. pylori seropositive and total bone mineral density.


Effect modifier	Model I (, 95% CI, )	Model II (, 95% CI, )	Model III (, 95% CI, )

Total	-0.015 (-0.025, -0.006) 0.001	-0.002 (-0.011, 0.007) 0.665	0.006 (-0.003, 0.015) 0.177
Age groups
40-55 years ()	-0.001 (-0.016, 0.013) 0.850	0.004 (-0.011, 0.019) 0.590	0.018 (0.004, 0.033) 0.012
~70 years ()	-0.019 (-0.035, -0.003) 0.0188	-0.014 (-0.029, 0.001) 0.064	-0.010 (-0.025, 0.004) 0.169
~85 years ()	0.007 (-0.012, 0.026) 0.487	0.008 (-0.008, 0.023) 0.329	0.009 (-0.007, 0.024) 0.257
Sex
Male ()	0.002 (-0.011, 0.015) 0.746	0.013 (-0.000, 0.026) 0.056	0.019 (0.007, 0.032) 0.003
Female ()	-0.031 (-0.044, -0.018) <0.001	-0.014 (-0.025, -0.002) 0.023	-0.002 (-0.014, 0.009) 0.730
Race
Non-Hispanic White ()	-0.023 (-0.039, -0.007) 0.004	-0.003 (-0.016, 0.010) 0.655	0.008 (-0.005, 0.021) 0.237
Non-Hispanic Black ()	-0.019 (-0.043, 0.006) 0.131	-0.018 (-0.039, 0.003) 0.100	-0.013 (-0.035, 0.008) 0.230
Mexican American ()	0.006 (-0.013, 0.025) 0.514	-0.004 (-0.020, 0.013) 0.672	0.003 (-0.014, 0.020) 0.703
Other races ()	0.018 (-0.013, 0.049) 0.256	0.024 (-0.004, 0.051) 0.089	0.015 (-0.010, 0.041) 0.244
BMI categories
Undernutrition ()	-0.081 (-0.199, 0.037) 0.188	0.020 (-0.093, 0.134) 0.728	-0.000 (-0.282, 0.281) 0.997
Normal ()	-0.015 (-0.034, 0.004) 0.131	0.001 (-0.017, 0.018) 0.951	0.017 (-0.001, 0.035) 0.064
Overweight ()	-0.010 (-0.026, 0.006) 0.234	0.005 (-0.009, 0.019) 0.515	0.007 (-0.007, 0.022) 0.304
Obese ()	-0.023 (-0.039, -0.007) 0.0056	-0.008 (-0.022, 0.006) 0.270	-0.003 (-0.017, 0.011) 0.668

Model I: no covariates were adjusted; model II: age, sex, and race were adjusted; model III: age, sex, race, educational level, body mass index, ratio of family income to poverty, physical activity, smoking behavior, hypertension status, diabetes status, coronary artery disease status, serum uric acid, total calcium, blood urea nitrogen, serum creatinine, total cholesterol, bone alkaline phosphatase, and dietary calcium intake were adjusted.