Curcumin Targeting NF-κB/Ubiquitin-Proteasome-System Axis Ameliorates Muscle Atrophy in Triple-Negative Breast Cancer Cachexia Mice

Figure 5

Curcumin alleviates mitochondrial dysfunction and increased ATP production in gastrocnemius of TNBC mice. (a–c) Transmission electron microscope observation of the gastrocnemius in the healthy group, the model group and the curcumin group (green: myofibrils; orange: sarcomere Z-line; blue: H band; reddish-brown: mitochondria; purple: edema; left: 20,000x magnification; right: 50,000x magnification). (d) Statistical analysis of ATP content in gastrocnemius tissue of mice in three groups (/group). and by -test, compared to the model group. Data were shown as .

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