Exploring the Relationship of Perivascular Adipose Tissue Inflammation and the Development of Vascular Pathologies

<div>Pathways involving perivascular adipose tissue (PVAT) inflammation in atherosclerosis. FFA: free fatty acid; H<sub>2</sub>S: hydrogen sulfide; IFN-<i>γ</i>: interferon-<i>γ</i>; IL: interleukin; IgM: immunoglobulin M; MCP-1: monocyte chemoattractant protein-1; MIP-1<i>α</i>: macrophage inflammatory protein 1-<i>α</i>; NO: nitric oxide; PIAS1: protein inhibitor of activated STAT1; RANTES: regulated on activation, normal T cell expressed, and secreted; ROS: reactive oxygen species; Taf3: TATA-box binding protein associated factor 3; TNF-<i>α</i>: tumor necrosis factor-alpha; Xpr1: xenotropic and polytropic retrovirus receptor 1.</div>

Mediators of Inflammation

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Figure 2: Exploring the Relationship of Perivascular Adipose Tissue Inflammation and the Development of Vascular Pathologies 