Prognostic Value of Albumin-to-Fibrinogen Ratio for 28-Day Mortality among Patients with Sepsis from Various Infection Sites

Table 4

Predictive valve of APACHE II score, lactic acid, septic shock, AFR, triple index, and quadruple index for 28-day mortality in patients with sepsis.

Variables	ROC area (AUC)	95% CI	Best threshold	Specificity	Sensitivity
APACHE II score	0.849	0.806~0.892	21.50	0.869	0.687
Lactic acid (mmol/L)	0.741	0.683~0.798	4.095	0.745	0.701
Septic shock	0.631	0.594~0.667	NA	0.275	0.986
AFR	0.700	0.641~0.758	5.860	0.908	0.421
Triple index	0.877	0.839~0.915	-0.412	0.778	0.823
Quadruple index	0.922	0.893~0.951	0.0024	0.869	0.836

ROC: receiver operating characteristic; AUC: area under the curve; APACHE II: Acute Physiology and Chronic Health Evaluation; AFR: albumin-to-fibrinogen ratio; Triple index includes APACHE II score, lactic acid, and septic shock; quadruple index includes APACHE II score, lactic acid, septic shock, and AFR; CI: confidence interval.