Research Article

ST3GAL3 Promotes the Inflammatory Response of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis by Activating the TLR9/MyD88 Pathway

Figure 2

ST3GAL3 promoted the proliferation of MH7A cells. (a, b) After MH7A cells were transfected with ST3GAL3 overexpression plasmid or ST3GAL3 siRNA, qRT-PCR was performed to show the gene expression of ST3GAL3. (c, d) Western blotting analysis was performed to show the protein expression of ST3GAL3. (e, f) MTT assay showed that ST3GAL3 overexpression promoted cell proliferation, while si-ST3GAL3 inhibited cell proliferation. (g, h) Western blotting analysis showed that the overexpression of ST3GAL3 promoted the protein expression of cyclinD, cyclinE, and PCNA, while si-ST3GAL3 inhibited the expression of those proteins. . , , and compared with the indicated group.
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