Research Article
C-Reactive Protein-to-Albumin Ratio as an Early Biomarker to Identify Sepsis in Neonates with Pneumonia
Table 1
Basic characteristics of study subjects by groups.
| | Variables | Nonsepsis group () | Sepsis group () | |
| | Age (days) | 7.0 (4.0, 13.0) | 11.0 (5.0, 17.0) | <0.001 | | Male, | 197 (59.0%) | 314 (61.2%) | 0.517 | | Weight (kg) | | | 0.025 | | Temperature (°C) | | | <0.001 | | Respiratory (rate/minute) | | | <0.001 | | Heart rate (bpm) | | | <0.001 | | SBP (mmHg) | | | 0.365 | | DBP (mmHg) | | | 0.594 | | Biochemical parameters | | | | | PCT (ng/ml) | 0.15 (0.10, 0.25) | 0.34 (0.14, 1.73) | <0.001 | | CRP (mg/l) | 0.7 (0.7, 0.7) | 0.7 (0.7, 17.6) | <0.001 | | ALT (U/l) | 25.6 (20.1, 33.3) | 29.0 (22.4, 39.0) | <0.001 | | AST (U/l) | 37.6 (30.0, 50.5) | 28.3 (27.9, 54.7) | 0.965 | | TP (g/l) | | | <0.001 | | ALB (g/l) | | | <0.001 | | CAR (×10-3) | 0.021 (0.019, 0.024) | 0.028 (0.023, 0.61) | <0.001 | | nSOFA | 0 (0, 0) | 0 (0, 2.0) | <0.001 | | Length of hospital stay (days) | 9.0 (8.0, 12.0) | 15.0 (11.0, 23.0) | <0.001 |
|
|
Abbreviations: SBP: systolic blood pressure; DBP: diastolic blood pressure; PCT: procalcitonin; CRP: C-reactive protein; ALT: alanine aminotransferase; AST: aspartate aminotransferase; TP: total protein; ALB: albumin; CAR: C-reactive protein-to-albumin ratio; nSOFA: neonatal sequential organ failure assessment.
|
