Association of Red Cell Distribution Width-to-Platelet Ratio and Mortality in Patients with Sepsis
Table 1
Comparison of baseline characteristics between 28-day survivors and nonsurvivors.
Variables
All patients ()
Survivors ()
Nonsurvivors ()
value
Age (years)
66 [55, 77]
65 [54, 77]
69 [58,79]
< 0.001
Marital, (%)
0.030
Married
1668 (49.5%)
1164 (48.4%)
504 (52.5%)
Not married
1699 (50.5%)
1243 (51.6%)
456 (47.5%)
Gender, (%)
0.099
Female
1450 (43.1%)
1058 (44.0%)
392 (40.8%)
Male
1917 (56.9%)
1349 (56.0%)
568 (59.2%)
Ethnicity, (%)
0.001
White
2449 (72.7%)
1756 (73.0%)
693 (72.2%)
Black
352 (10.5%)
274 (11.4%)
78 (8.1%)
Other
566 (16.8%)
377 (15.7%)
189 (19.7%)
BMI (kg/m2)
27 [23, 32]
27 [24, 33]
27 [23, 32]
0.056
Temperature (°C)
37 [36, 37]
37 [36, 37]
37 [36, 37]
< 0.001
SpO2 (%)
97 [96, 99]
97 [96, 99]
97 [96, 99]
< 0.001
Renal replacement therapy, (%)
0.001
No
3074 (91.3%)
2222 (92.3%)
852 (88.8%)
Yes
293 (8.7%)
185 (7.7%)
108 (11.3%)
Mechanical ventilation, (%)
< 0.001
No
1586 (47.1%)
1223 (50.8%)
363 (37.8%)
Yes
1781 (52.9%)
1184 (49.2%)
597 (62.2%)
Vasopressor use, (%)
< 0.001
No
997 (29.6%)
814 (33.8%)
183 (19.1%)
Yes
2370 (70.4%)
1593 (66.2%)
777 (80.9%)
Albumin (g/dL)
3 [2, 3]
3 [2,3]
3 [2, 3]
< 0.001
Bicarbonate (mEq/L)
22 [19, 25]
22 [19, 25]
21 [18, 25]
< 0.001
Anion gap (mEq/L)
15 [13,18]
15 [13, 17]
16 [14,19]
< 0.001
Creatinine (mg/dL)
1 [1, 2]
1 [1, 2]
2 [1, 3]
< 0.001
Bilirubin (mg/dL)
1 [0, 2]
1 [0, 2]
1 [1, 3]
< 0.001
Chloride (mEq/L)
105 [101, 109]
106 [102, 110]
104 [100, 109]
< 0.001
Glucose (mg/dL)
134 [110, 169]
134 [110, 168]
135 [110, 171]
0.772
Hematocrit (%)
31 [28, 35]
31 [28, 35]
30 [27, 34]
0.048
Hemoglobin (g/dL)
10 [9, 12]
10 [9, 12]
10 [9, 11]
0.012
Sodium (mEq/L)
138 [135, 141]
139 [135, 141]
138 [134, 141]
0.006
Potassium (mEq/L)
4 [4, 5]
4 [4, 5]
4 [4, 5]
< 0.001
BUN (mg/dL)
29 [18, 49]
27 [17, 45]
37 [23, 58]
< 0.001
WBC (109/L)
13 [9, 19]
13 [9, 19]
13 [8, 19]
0.281
Lactate (mmol/L)
2 [1, 3]
2 [1, 3]
2 [2, 4]
< 0.001
PT (seconds)
16 [14, 19]
15 [14, 18]
16 [14, 21]
< 0.001
INR (seconds)
1 [1, 2]
1 [1, 2]
2 [1, 2]
< 0.001
Lymphocyte (%)
8 [4, 14]
9 [5, 15]
7 [3, 12]
< 0.001
Neutrophil (%)
82 [73, 89]
81 [72, 88]
83 [73, 90]
0.004
RPR
1 [1, 1]
1 [1, 1]
1 [1, 1]
< 0.001
Congestive heart failure, (%)
0.001
No
2118 (62.9%)
1558 (64.7%)
560 (58.3%)
Yes
1249 (37.1%)
849 (35.3%)
400 (41.7%)
Hypertension, (%)
0.550
No
1621 (48.1%)
1151 (47.8%)
470 (49.0%)
Yes
1746 (51.9%)
1256 (52.2%)
490 (51.0%)
Diabetes, (%)
0.833
No
2225 (66.1%)
1588 (66.0%)
637 (66.4%)
Yes
1142 (33.9%)
819 (34.0%)
323 (33.6%)
SOFA
7 [4, 10]
8 [6, 11]
6 [4, 9]
< 0.001
SAPS II
44 [34, 54]
51 [42, 61]
41 [32, 51]
< 0.001
BMI: body mass index; SpO2: oxygen saturation; BUN: blood urea nitrogen; WBC: white blood cell; PT: prothrombin time; INR: international normalized ratio; RPR: red cell distribution width to platelet ratio; SOFA: sequential organ failure assessment; SAPS II: simplified acute physiology score II.
