Association of Red Cell Distribution Width-to-Platelet Ratio and Mortality in Patients with Sepsis

Table 3

Risk of 28-day mortality in patients with sepsis according to red cell distribution width to platelet ratio.

Model	Continuous variables		Categorical variable; (≥ 0.109 vs. < 0.109)
	HR (95% CI)	value	HR (95% CI)	value
Crude model	2.897 (2.216-3.788)	< 0.001	1.607 (1.415-1.825)	< 0.001
Model 1 ^a	3.724 (2.846-4.872)	< 0.001	1.668 (1.468-1.895)	< 0.001
Model 2 ^b	3.724 (2.846-4.872)	< 0.001	1.699 (1.493-1.932)	< 0.001
Model 3 ^c	3.762 (2.761-5.126)	< 0.001	1.322 (1.149-1.522)	< 0.001
Model 4 ^d	3.404 (2.483-4.666)	< 0.001	1.303 (1.132-1.500)	< 0.001
Model 5 ^e	2.826 (2.025-3.944)	< 0.001	1.210 (1.045-1.400)	0.011

HR: hazard ratio; CI: confidence interval; ^a Model 1 was adjusted for demographic information, including age, gender, marital status, and ethnicity; ^b Model 2 also adjusted for complications including congestive heart failure, hypertension, and diabetes; ^c Model 3 additionally adjusted laboratory tests, including albumin, bicarbonate, anion gap, creatinine, bilirubin, chloride, glucose, hematocrit, hemoglobin, sodium, potassium, blood urea nitrogen, white blood cell, lactate, prothrombin time, international normalized ratio, lymphocyte, and neutrophil; ^d Model 4 made additional adjustments to clinical treatment, including renal replacement therapy, mechanical ventilation, and vasopressor use; ^e Model 5 additionally adjusted the scoring system, including sequential organ failure assessment and simplified acute physiology score II.