Predictive Role of IL-2R and IL-10 in the Anti-inflammatory Response and Antiplatelet Therapy of Kawasaki Disease: A Retrospective Study

Figure 3

Association between altered levels of IL-2R and IL-10 and the percentages of CD8⁺ T and CD19⁺ B cells in all children with KD during KD and the distribution of KD children treated with clopidogrel between children with KD who were <4 years and children with KD who were ≥4 years. (a) Decreased levels of IL-2R were negatively correlated with the percentage of CD8⁺ T cells in children with KD. (b) Decreased levels of IL-2R were positively correlated with the percentage of CD19⁺ B cells in children with KD. (c) The extent of the decrease of IL-2R was positively correlated with that of IL-10. (d) The extent of the decrease of IL-10 was positively correlated with the percentage of CD19⁺ B cells in children with KD. (e) The mean value of the ratio of IL-2R/IL-10 before IVIG treatment was lower than that after IVIG (), which were, respectively, and . (f) There was no difference in the number of children with KD treated with clopidogrel between patients who were <4 years old and patients who were ≥4 years old.

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