First author Year Region Design Sample size Mean age Gender (percentage of males) Main result Aslan [25 ] 2020 Turkey Retrospective Total: 170 Patients: 113 Controls: 57 Patients: Controls: Patients: 55 (48.7%) Controls: 32 (56.1%) There was significantly higher NLR in epileptic patients compared to the healthy controls. Baran [24 ] 2020 Turkey Retrospective Total: 71 Patients: 36 Controls: 35 Patients: Controls: Patients: 20 (55.5%) Controls: 19 (54.28%) NLR was not significantly different between patients and healthy controls. Güneş [23 ] 2020 Turkey Retrospective Total: 144 Patients: 72 Controls: 72 Patients: Controls: Patients: 35 (48.6%) Controls: 36 (50%) The probability of epileptic seizure increased 1.954 times for every unit rise in NLR during the acute phase and 1.731 times for every unit rise in NLR during the subacute phase. Özdemir [13 ] 2016 Turkey Retrospective Total: 116 Patients: 58 Controls: 58 Patients: Controls: Patients: 26 (44.8%) Controls: 31 (53.4%) NLR was not significantly different between patients with convulsive status epilepticus and healthy controls. Morkavuk [4 ] 2020 Turkey Prospective Total: 50 Epilepsy: 36 PNES: 14 Epilepsy patients: 26.5 (18.5-48.3) PNES group: 33.5 (18–56) Epilepsy patients: 23 (64%) PNES group: 4 (29%) NLR is not a good biomarker for differentiating between patients with epileptic seizures and those with pseudoseizures. Ozdemir [26 ] 2019 Turkey Prospective Total: 42 Patients: 21 Controls: 21 Patients: Controls: Patients: 9 (42%) Controls: 13 (61%) Surgery for temporal lobe epilepsy resulted in large increases in NLR, and NLR was significantly higher after surgery compared to before surgery samples of patients. Eroglu [27 ] 2017 Turkey Retrospective Total: 101 Patients: 52 Controls: 49 Patients: Controls: Patients: 20 (38.5%) Controls: 19 (38.8%) NLR was not significantly different between patients and healthy controls.