miR-181d-5p Protects against Retinal Ganglion Cell Death after Blunt Ocular Injury by Regulating NFIA-Medicated Astrocyte Development

Figure 3

miR-181d-5p relieves RGCs death, astrocyte development, oxidative stress, and inflammation of the retina. (a) Expression of miR-181d-5p by RT-qPCR detection. (b) Representative images of retinal tissues stained by H&E ( μm). (c) Representative images of POU-homeodomain transcription factor Brn3a staining ( μm). (d) GFAP staining ( μm). (e) SOD activity. (f) MDA content. (g) Western blot assay of Bcl-2 and Bax protein. (h) Proinflammatory factor levels were measured by ELISA. , , and vs. the sham group; ^#, ^##, and ^### vs. the model group.

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