Combination of White Blood Cell Count to Mean Platelet Volume Ratio and Neutrophil-to-Platelet Ratio Predicts Long-Term Adverse Events in Patients with MINOCA

Table 3

Results of Cox proportional-hazards regression analysis.

	Hazard ratio	95% CI	value
Model A—WMR ≤ 701 vs. > 701
WMR>701	2.155	1.196-3.881	0.011
Age	1.031	1.007-1.056	0.012
AF	2.286	1.108-4.715	0.025
LVEF	0.979	0.959-0.999	0.052
Model B—NPR ≤ 0.03 vs. > 0.03
NPR>0.03	1.831	1.036-3.235	0.037
Age	1.028	1.003-1.054	0.030
LVEF	0.978	0.958-0.999	0.038
Model C—combination of WMR and NPR
Age	1.027	1.002-1.053	0.033
Low WMR and low NPR	Reference	Reference
Either low WMR or low NPR	1.479	0.673-3.248	0.330
High WMR and high NPR	2.511	1.271-4.960	0.008

Abbreviations: WMR: white blood cell count to mean platelet volume ratio; NPR: neutrophil-to-platelet ratio; AF: atrial fibrillation; LVEF: left ventricular ejection fraction; CI: confidence interval. Models adjusted for age, sex, smoking, hypertension, diabetes mellitus, hyperlipidemia, atrial fibrillation, left ventricular ejection fraction, and the degree of coronary stenosis.