Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis

<div>OI decreased Con A-induced hepatocyte apoptosis and oxidative stress in liver. Representative images for (a, b) positive TUNEL cells and immunohistochemical assay of (c, d) c-PARP were evaluated in hepatic tissues in each group. The (e) GSH/GSSG ratio and (f) MDA levels were measured in hepatic tissues in each group. 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Mediators of Inflammation

fig3

Figure 3

Figure 3: Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis 