MFG-E8 Knockout Aggravated Nonalcoholic Steatohepatitis by Promoting the Activation of TLR4/NF-κB Signaling in Mice

Figure 6

Effect of MFG-E8 knockout on hepatic inflammatory mediators in NASH mice. (a) TNF-α and (b) IL-1β protein levels in the liver were detected by ELISA. (c) The mRNA levels of hepatic TNF-α, IL-1β, IL-6, ICAM, CCL2, CXCL2, and TGF-β were measured by RT-qPCR. Data were expressed as , , ^## compared with CD-WT group; , compared with MCD-WT group.

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