Using Network Pharmacology and Animal Experiment to Investigate the Therapeutic Mechanisms of Polydatin against Vincristine-Induced Neuropathic Pain

<div>Identification of hub genes. Eight algorithms (stress, betweenness, closeness, degree, DMNC, EPC, MNC, and radiality) were used to identify hub genes based on R package “UpSet.”</div>

Mediators of Inflammation

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Figure 4: Using Network Pharmacology and Animal Experiment to Investigate the Therapeutic Mechanisms of Polydatin against Vincristine-Induced Neuropathic Pain 

Figure 4 | Using Network Pharmacology and Animal Experiment to Investigate the Therapeutic Mechanisms of Polydatin against Vincristine-Induced Neuropathic Pain 