Role of P2X4/NLRP3 Pathway-Mediated Neuroinflammation in Perioperative Neurocognitive Disorders

Figure 2

5-BDBD suppressed surgery-induced cognitive impairment. (a) Escape latency and (b) swimming speed in the acquisition procedure. The data are presented as (). CON group vs. SUR group; ^# SUR group vs. group. (b) The surgery did not affect the swimming speed of the mice. (c) Crossing-platform times, (d) dwelling time, and (e) the percentage of distance in the target quadrant in the probe trial. The data are presented as (); , . (f) Representative swimming path of four groups in the probe test.

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