Crosstalk between the Gut and Brain in Ischemic Stroke: Mechanistic Insights and Therapeutic Options

Figure 1

An illustration of the MGBA in the healthy individual. In ENS, the gut microbiota affects how the brain works by releasing various signal molecules that may go to target areas through systemic circulation. Through the ANS, the CNS physiologically controls the GI tract; in turn, the gut provides feedback to the brain to establish a bidirectional link.