Sodium Butyrate Attenuates Diabetic Kidney Disease Partially via Histone Butyrylation Modification

Figure 3

NaB induces histone Kbu in DKD kidney and renal mesangial cells. Immunohistochemistry (400x)-based assays for the expression of PanKbu and H3K9bu in DKD kidney tissue after NaB treatment (a). The expression of PanKbu in kidneys of each group was detected by immunofluorescence (×400) (b). The expression of PanKbu and H3K9bu after different concentrations of NaB intervened in GMCs (c). The expression of PanKbu and H3K9bu in GMCs of each group (d). The expression of H3K9bu in the nucleus in each group of GMCs (e). Values are presented as the . .

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