Research Article
The Role of the Monocyte-to-Lymphocyte Ratio in Acute Ischemic Stroke Patients with Acute Kidney Injury
Table 1
Subjects’ initial features and outcomes.
| | Variables | ALL () | Patients with AKI () | Patients without AKI () | value |
| | Male (%) | 361 (60.7%) | 91 (68.4%) | 270 (58.4%) | 0.000 | | Age (years) | | | | 0.823 | | Comorbidities | | | | | | Hypertension | 436 (73.4%) | 107 (80.5%) | 329 (71.4%) | 0.037 | | Diabetes | 136 (22.9%) | 43 (32.3%) | 93 (20.2%) | 0.003 | | Coronary artery disease | 148 (24.9%) | 41 (30.8%) | 107 (23.2%) | 0.071 | | COPD | 13 (2.2%) | 7 (5.3%) | 6 (1.3%) | 0.016 | | eGFR (ml/min/1.73m2) | | | | 0.000 | | Laboratory index at NICU admission | | | | | | Baseline Scr (umol/l) | | | | 0.000 | | BUN (mmol/l) | | | | 0.000 | | Albumin (g/l) | | | | 0.364 | | Triglyceride (mmol/l) | | | | 0.087 | | PCT (ng/ml) | 0.24 (0.07, 0.55) | 0.54 (0.80, 0.72) | 0.08 (0.05, 0.16) | 0.001 | | White blood count/mm3 | | | | 0.314 | | CRP | 11.29 (2.10,18.87) | 25.78 (17.02,131.59) | 8.47 (4.6, 56.08) | 0.002 | | Haemoglobin | | | | 0.005 | | NIHSS score | | | | <0.001 | | GCS score | | | | 0.000 | | PLR | | | | <0.001 | | MLR | | | | <0.001 | | NLR | | | | <0.001 | | Neutrophils | | | | 0.356 | | Lymphocytes | | | | 0.092 | | Monocytes | | | | 0.006 | | Platelets | | | | 0.228 | | Outcome | | | | | | In-hospital mortality | 11 | 4 (3.0%) | 7 (1.5%) | 0.026 | | RRT | 2 | 2 (1.5%) | 0 | 0.000 | | Ventilation | 43 (7.23%) | 17 (12.8%) | 26 (5.6%) | 0.005 | | Hospital stay | | | | 0.024 |
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MLR: monocyte-to-lymphocyte ratio; PLR: platelet-to-lymphocyte ratio; NIHSS: National Institutes of Health Stroke Scale score; GCS: Glasgow coma score; Scr: serum creatinine; RRT: renal replacement treatment; COPD: chronic obstructive pulmonary disease; CRP: C-reactive protein; PCT: procalcitonin; NLR: neutrophil-to-lymphocyte ratio; HGB: haemoglobin.
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