Ameliorative Effect of Curcumin Nanoparticles against Monosodium Iodoacetate-Induced Knee Osteoarthritis in Rats

Table 2

Effect of CUR-loaded PLGA NPs on the serum levels of TNF-α, IL-1β, IL-6, TGF-β, and IL-10 in MIA-induced OA in rats.

Groups	Parameters
	TNF-α (pg/mL)	IL-1β (pg/mL)	IL-6 (pg/mL)	TGF-β (pg/mL)	IL-10 (pg/mL)
Normal control	^a	^a	^a	^a	^c
MIA	^c	^c	^c	^c	^a
MIA+CUR-loaded PLGA NPs	^b	^b	^b	^b	^b

There were six samples in each group, and data are described as . For each parameter, means, which have different superscript symbols, are statistically significant at .