Arsenic Induces Continuous Inflammation and Regulates Th1/Th2/Th17/Treg Balance in Liver and Kidney In Vivo

Figure 4

Suchronic arsenic exposure affected the expression of CD4⁺ T cell-specific signature cytokines in the liver and kidney. Mice were treated with 25 and 50 mg/L NaAsO₂ by drinking water for 1 and 3 months. The mRNA levels of T cell signature cytokines IFN-γ, IL-13, IL-23, and IL-10 in the liver (a–d) and kidney (e–h) were determined by real-time PCR; the ratios of IFN-γ/IL-13 and IL-23/IL-10 were calculated in liver (i–j) and kidney (k–l). Data were expressed as . compared with control mice.

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