Research Article
Atractylenolide III Improves Mitochondrial Function and Protects Against Ulcerative Colitis by Activating AMPK/SIRT1/PGC-1α
Figure 5
AT III abrogates LPS-induced epithelial barrier impairment in IEC-6 cells. (a) Paracellular permeability was measured using FITC-dextran. (b, c) Western blots for occludin and ZO-1 proteins and quantification results. (d, e) Representative images of occludin were determined and quantified by immunofluorescence. (f, g) Representative images of ZO-1 were measured and quantified by immunofluorescence. Scale bar: 50 μm. $, compared to control; &, compared to LPS.
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |
(g) |