Mediators of Inflammation

Research Article

Predictive Values of Serum IL-33 and sST2 in Endotypes and Postoperative Recurrence of Chronic Rhinosinusitis with Nasal Polyps

Table 4

Unadjusted and adjusted multivariate logistic regression analysis of factor associated with eCRSwNP. Resutls were adjusted for age, gender, smoking, BMI, atopy, allergic rhinitis, asthma and Lund-Mackay score, Lund-Kennedy score, and VAS score.


Factor	Unadjusted		Adjusted
Factor	OR (95% CI)		OR (95% CI)

Atopy	1.272 (0.985-2.765)	0.768	1.387 (0.913-2.986)	0.812
Allergic rhinitis	1.784 (1.152-3.869)	0.030	1.591 (0.938-3.024)	0.077
Asthma	2.053 (1.287-4.876)	0.042	1.867 (1.319-4.767)	0.016
B-EOS count (10⁶/L)	1.479 (1.176-2.954)	0.029	1.381 (0.897-2.482)	0.164
B-EOS percentage (%)	1.985 (1.358-5.897)	0.008	2.323 (1.786-6.056)	0.019
Serum IL-33 level (pg/mL)	2.871 (1.674-8.992)	0.005	2.732 (1.476-9.568)	0.001
Serum ST2 level (ng/mL)	2.439 (1.176-7.569)	<0.001	2.856 (1.285-8.789)	<0.001

eCRSwNP: eosinophilic chronic rhinosinusitis with nasal polyps; B-EOS: blood eosinophil; ST2: suppressor of tumorigenicity 2; OR: odds rate; CI: confidence interval.