Expression of Thymic Stromal Lymphopoietin in Immune-Related Dermatoses
Table 1
Inclusion criteria for specimens used in retrospective analysis.
Disease
Inclusion criteria
LP
Typical clinical manifestation + wedge-shaped hypergranulosis, dense band-like lymphocytic infiltrate with an absence of eosinophils or parakeratosis
DLE
Clinical suspicion + hyperkeratosis, vacuolar interface change, thickened basement membrane with patchy superficial and deep lymphocytic infiltrate
Eczema
Clinical suspicion + spongiosis with superficial perivascular inflammatory infiltrate, and without clear aetiology, not atopic dermatitis or contact dermatitis
BP
Clinical suspicion + subepidermal blister with direct or indirect immunofluorescence and/or autoantibodies
PsV
Clinical suspicion + confluent parakeratosis with regular acanthosis
Sarcoidosis
Clinical suspicion + “naked” granulomas with no/minimal lymphocytes surrounding granuloma, rule tuberculosis and leprosy out
MF
Clinical suspicion + epidermotropic lymphocytes, intraepidermal collections of lymphocytes, atypical lymphocytes, typical immunophenotype with clonal TCR rearrangement
