Cell-Free DNA, Neutrophil extracellular traps (NETs), and Endothelial Injury in Coronavirus Disease 2019– (COVID-19–) Associated Acute Kidney Injury

Table 2

Diagnostic performance of cell-free DNA (cfDNA) for predicting severe acute.

cfDNA
	Cutoff (ng/mL)	Sensitivity	Specificity	AUC (95% CI)
Severe AKI	161.3	0.67	0.92	0.82 (0.67-0.97)
Need for RRT	142.0	0.75	0.77	0.76 (0.54-0.98)

AKI, acute kidney injury; AUC, area under the curve; CI, confidence interval; cfDNA, cell-free DNA; RRT, renal replacement therapy.