Research Article

Association between ALT/AST and Muscle Mass in Patients with Type 2 Diabetes Mellitus

Table 1

The characteristics of patients with and without low muscle mass.

CharacteristicsMale ()Female ()
Normal muscle mass ()Low muscle mass
()
valueNormal muscle mass
()
Low muscle mass
()
value

Age (years)<0.0010.002
Smoking0.6400.999
 No ()2115142670
 Yes ()2406451
Drinking0.9320.999
 No()2536442971
 Yes()1985120
Duration (years)7.0 (4.0,10.0)8.0 (6.0,12.0)0.0068.0 (5.0,10.0)8.0 (5.0,10.0)0.932
BMI (kg/m2)<0.001<0.001
SMI(kg/m2)<0.001<0.001
SBP (mmHg)0.1370.779
DBP (mmHg)0.0060.994
TG (mmol/L)1.63 (1.05,2.46)1.10 (0.85,1.83)<0.0011.47 (1.03,2.15)1.32 (0.86,1.62)0.002
TC (mmol/L)0.7240.624
LDL (mmol/L)0.9580.445
HDL (mmol/L)0.0110.136
FPG (mmol/L)0.6040.037
HbA1c (%)0.0280.528
ALT(U/L)19.0 (14.0,28.0)15.0 (11.0,21.0)<0.00116.0 (12.0,22.0)14.0 (11.0,20.0)0.066
AST(U/L)17.0 (14.0,22.0)16.0 (13.0,20.0)0.00316.0 (13.0,20.0)18.0 (14.0,20.0)0.402
ALT/AST0.87 (0.68,1.07)1.00 (0.82,1.26)<0.0011.00 (0.80,1.20)1.09 (0.96,1.38)<0.001