Research Article

CLDN4 as a Novel Diagnostic and Prognostic Biomarker and Its Association with Immune Infiltrates in Ovarian Cancer

Table 1

Association of CLDN4 expression levels with clinical factors in ovarian cancer patients.

CharacteristicLow expression of CLDN4High expression of CLDN4

189190
Age, (%)1.000
 ≤60104 (27.4%)104 (27.4%)
 >6085 (22.4%)86 (22.7%)
FIGO stage, (%)0.203
 Stage I0 (0%)1 (0.3%)
 Stage II14 (3.7%)9 (2.4%)
 Stage III150 (39.9%)145 (38.6%)
 Stage IV23 (6.1%)34 (9%)
Histologic grade, (%)0.269
 G11 (0.3%)0 (0%)
 G219 (5.1%)26 (7%)
 G3165 (44.7%)157 (42.5%)
 G40 (0%)1 (0.3%)
Lymphatic invasion, (%)0.817
 No23 (15.4%)25 (16.8%)
 Yes52 (34.9%)49 (32.9%)
 Age, median (IQR)59 (50, 69)58.5 (52, 67)0.786