BCL-3 Promotes Intracerebral Hemorrhage Progression by Increasing Blood–Brain Barrier Permeability, Inflammation, and Cell Apoptosis via Endoplasmic Reticulum Stress

Figure 5

Effect of BCL-3 knockdown on BBB permeability and ERS, reducing inflammation in vivo. (a) qRT-PCR was performed to measure the BCL-3 expression on the brain. (b) H&E staining demonstrating the histopathology of the brain. (c) BBB permeability was evaluated by Evans blue staining. (d) The tight junction proteins of occludin and claudin-5 measured by qRT-PCR. (e) The inflammation factors of IL-1, IL-6, and TNF-α in the serum. (f) Apoptosis was evaluated by TUNEL. (g) ERS-related proteins were measured by western blotting.

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