Research Article

Investigation of the Effects of Some Cardiovascular Drugs on Angiogenesis by Transgenic Zebrafish

Figure 2

Chemical screen to identify angiogenic drugs in cardiovascular medicine. (a) Bright-field and fluorescent images of zebrafish embryos in 24 hpf treated with 0.5% DMSO (control) and 200 ng/ml VEGF (positive control) for 24 h. (b) Amlodipine-, isosorbide mononitrate-, and bisoprolol-treated embryos are shown. (c) Average ISV numbers and lengths in the control and drug-treated zebrafish embryos. Values for the average ISV numbers and lengths are present as . vs. control group.
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