Association of Systemic Immune Inflammation Index with Estimated Pulse Wave Velocity, Atherogenic Index of Plasma, Triglyceride-Glucose Index, and Cardiovascular Disease: A Large Cross-Sectional Study
Table 4
Subgroup analysis for the associations of SII index with the prevalence of total CVD.
Q1
Q2
Q3
Q4
for trend
for interaction
OR (95% CI)
OR (95% CI)
OR (95% CI)
OR (95% CI)
Age
<0.001
<60
1.00
0.911 (0.746, 1.316)
0.815 (0.610, 1.089)
1.036 (0.789, 1.360)
0.343
≥60
1.00
0.920 (0.758, 1.118)
1.051 (0.871, 1.268)
1.259 (1.052, 1.507)
0.005
Gender
0.005
Male
1.00
0.824 (0.664, 1.023)
0.974(0.790, 1.200)
1.092(0.892, 1.337)
0.068
Female
1.00
1.050 (0.819, 1.345)
0.892 (0.698, 1.140)
1.135 (0.902, 1.428)
0.194
Race/ethnicity
0.011
Mexican American
1.00
1.117 (0.699, 1.785)
0.936 (0.580, 1.512)
1.730 (1.096, 2.731)
0.021
Other Hispanic
1.00
0.731 (0.397, 1.349)
0.897 (0.448, 1.647)
0.945 (0.525, 1.702)
0.769
Non-Hispanic Black
1.00
0.838 (0.604, 1.1620
0.787 (0.563, 1.101)
1.073 (0.768, 1.501)
0.295
Non-Hispanic White
1.00
0.945 (0.746, 1.197)
0.976 (0.779, 1.223)
1.013 (0.817, 1.256)
0.921
Other race
1.00
1.149 (0.563, 2.345)
1.351 (0.644, 2.835)
2.042 91.024, 4.075)
0.201
Hypertension
<0.001
No
1.00
1.009 (0.726, 1.401)
1.147 (0.834, 1.578)
1.229 (0.897, 1.684)
0.507
Yes
1.00
0.902 (0.749, 1.087)
0.889 (0.741, 1.066)
1.094 (0.921, 1.299)
0.055
DM
0.033
No
1.00
0.920 (0.749, 1.130)
0.906 (0.742, 1.105)
1.113 (0.921, 1.345)
0.120
Yes
1.00
0.918 (0.706, 1.195)
0.999 (0.770, 1.298)
1.112 (0.867, 1.426)
0.490
BMI
0.082
<30 kg/m2
1.00
0.935 (0.755, 1.157)
0.943 (0.765, 1.161)
1.154 (0.946, 1.408)
0.123
≥30 kg/m2
1.00
0.907 (0.706, 1.163)
0.943 (0.738, 1.204)
1.064 (0.842, 1.345)
0.544
Abbreviations: Q1: 1.529-330.179; Q2: 330.180-463.273; Q3: 463.274-654.615; Q4: 654.616-28397.276; SII: systemic immune inflammation; ; OR: odd ratio; CI: confidence interval. Analysis was adjusted for age, gender, race/ethnicity, education level, marital status, family poverty-income ratio, hypertension, diabetes mellitus, smoker, alcohol user, body mass index, waist circumference, hemoglobin, fast glucose, high-density lipoprotein cholesterol, total cholesterol, and triglyceride.
