HMGB2 Deficiency Mitigates Abdominal Aortic Aneurysm by Suppressing Ang-II-Caused Ferroptosis and Inflammation via NF-κβ Pathway

Figure 1

HMGB2 was enhanced in AAA. The expression of HMGB2 was assessed by RT-qPCR and western blot in Ang-II perfused aortas in Apoe^−/− mice (a and b). RT-qPCR and western blot were utilized to measure HMGB2 level in Ang-stimulated VSMCs (c and d). The level of HMGB2 was measured in human AAA tissues and normal aortas (e and f).

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