ANGPTL2 Deletion Attenuates Neuroinflammation and Cognitive Dysfunction Induced by Isoflurane in Aged Mice through Modulating MAPK Pathway

Figure 3

Downregulation of ANGPTL2 suppressed isoflurane-induced inflammation in mice. (a) TNF-α, IL-6, and IL-1β mRNA levels were detected using qRT-PCR. (b) ELISA was used to examine TNF-α, IL-6, and IL-1β levels in brain tissues. (c) Western blotting was used to measure p-NF-κB p65, NF-κB p65, and β-actin protein levels. . ; .

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