The Spliceosome Factor EFTUD2 Promotes IFN Anti-HBV Effect through mRNA Splicing

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td class="align_left">sgRNA</td><td class="align_center">Sequence (5<svg height="7.86364pt" id="M1" style="vertical-align:-0.04981995pt" version="1.1" viewbox="-0.0498162 -7.81382 4.53621 7.86364" width="4.53621pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M295 534L291 558C277 573 202 603 180 597L75 72L120 51L295 534Z"></path></g></svg>⟶3<span class="nowrap"><svg height="7.86364pt" id="M2" style="vertical-align:-0.04981995pt" version="1.1" viewbox="-0.0498162 -7.81382 4.53621 7.86364" width="4.53621pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M295 534L291 558C277 573 202 603 180 597L75 72L120 51L295 534Z"></path></g></svg>)</span></td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td class="align_left">EFTUD2 sgRNA1-F<br/>EFTUD2 sgRNA1-R</td><td class="align_center">CACCG GCACCACCTCCATCCCAGGG<br/>AAAC CCCTGGGATGGAGGTGGTGCC</td></tr><tr><td class="align_left">EFTUD2 sgRNA2-F<br/>EFTUD2 sgRNA2-R</td><td class="align_center">CACCG GCAGGTACATCAGGAGGACAT<br/>AAAC ATGTCCTCCTGATGTACCTGCC</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>SgRNAs targeted to exon3 of EFTUD2 gene.</div>

Mediators of Inflammation

tab1

Table 1

Table 1: The Spliceosome Factor EFTUD2 Promotes IFN Anti-HBV Effect through mRNA Splicing 