Identification of WD-Repeat Protein 72 as a Novel Prognostic Biomarker in Non-Small-Cell Lung Cancer

Table 3

Univariate and multivariate analysis of prognostic factors of 5-year overall survival in WDR 72 patients.

Characteristic	Univariate analysis			Multivariate analysis
	HR	95% CI		HR	95% CI
WDR72 expression
Low vs. high	0.478	0.328~0.752	<0.001	0.624	0.404~0.963	0.033
Gender
Male vs. female	0.706	0.471~1.057	0.091
Age (years)
≤60 vs. >60	0.925	0.617~1.386	0.705
Smoking
No vs. yes	0.605	0.402~0.910	0.016	0.885	0.546~1.432	0.618
Tumor size (cm)
≤3 vs. >3	0.342	0.220~0.530	<0.001	0.827	0.495~1.381	0.468
TNM stage
I/II vs. III/VI	0.219	0.144~0.332	<0.001	0.416	0.263~0.660	<0.001
Histology stage
Well vs. poorly	0.356	0.232~0.548	<0.001	0.417	0.257~0.677	<0.001
Metastasis
No vs. yes	0.192	0.124~0.298	<0.001	0.240	0.149~0.387	<0.001

HR: hazard ratio; CI: confidence interval; ; .