lncRNA MIR503HG Targets miR-191-5p/PLCD1 Axis and Negatively Modulates Apoptosis, Extracellular Matrix Disruption, and Inflammation in Abdominal Aortic Aneurysm

Figure 5

MIR503HG influenced AAA progression via miR-191-5p/PLCD1. (a) qRT-PCR assessed miR-191-5p inhibitor efficiency in VSMCs. (b–f) The viability and apoptotic capacities of VSMCs in four differently transfected groups were analyzed. (g, h) The levels of proliferation/apoptosis-correlated proteins and proteins associated with ECM degradation in each treatment group were detected. (i, j) Serum levels of the inflammatory cytokines in 4 groups were quantified. Three biological replicates were involved for each experiment. .

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