Research Article
Identifying Macrophage-Related Genes in Ulcerative Colitis Using Weighted Coexpression Network Analysis and Machine Learning
Figure 9
Validation in a 3% DSS-induced acute colitis mouse model and biospecimens. (a) Schematic of the 3% DSS-induced acute ulcerative colitis model. (b) Determination of the length of the colon in mice. (c) Representative images of H&E-stained colonic tissue at day 9 of colitis induction. (d and e) The relative expression levels of HMGCS2, ARG1, CD86, iNOS, and CD206 were measured by western blotting in the colonic tissues from DSS-induced colitis model and control mice. (f) Expression of SLC6A14 determined by IHC in six pairs of normal and UC colon tissues (, , in t-test).
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