Research Article
MALAT1 Mediates α-Synuclein Expression through miR-23b-3p to Induce Autophagic Impairment and the Inflammatory Response in Microglia to Promote Apoptosis in Dopaminergic Neuronal Cells
Figure 1
Differential expression of MALAT1, miR-23b-3p, and α-synuclein in damaged dopaminergic neuronal cells. (a) Apoptosis of dopaminergic neurons in MN9D cells was detected by flow cytometry, vs. control. (b) The expressions of Bcl-2, Bax, and Caspase 3 were detected by western blot, and vs. control. (c, d) The expressions of MALAT1 and miR-23b-3p were detected by RT-qPCR, vs. control. (e) The protein expression of α-synuclein was detected by western blot, vs. control. (f) The level of α-synuclein was detected by ELISA, vs. control.
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