Research Article

Matrix Metalloproteinase-7 Associated with Congestive Heart Failure in Peritoneal Dialysis Patients: A Prospective Cohort Study

Table 4

Cox regression analysis for PD withdrawal and combined endpoint.

VariablesPD withdrawalCombined endpoint
HR (95% CI)aHR (95% CI)b

Serum MMP7, ng/ml1.090 (1.028-1.550)0.0041.083 (1.011-1.580)0.02
Ln dialysate MMP7, pg/ml1.468 (1.152-1.870)0.0021.532 (1.131-2.076)0.006

KT/V was calculated by the formulas mentioned before. PD: peritoneal dialysis; MMP7: matrix metalloproteinase-7; HR: hazard ratio; CI: confidence interval; DKD: diabetic kidney disease; ESRD: end-stage renal disease. aAdjusted with demographics (age and sex), the mean values of dialysate glucose concentration, urine volume, serum creatinine, serum phosphate, hemoglobin, and KT/V during the first 12 months after dialysis. bAdjusted with demographics (age and sex), DKD to ESRD, the mean values of dialysate glucose concentration, urine volume, serum albumin, serum phosphate, hemoglobin, and KT/V during the first 12 months after dialysis.