Tumor Necrosis Factor-α Promotes the Tumorigenesis, Lymphangiogenesis, and Lymphatic Metastasis in Cervical Cancer via Activating VEGFC-Mediated AKT and ERK Pathways

Figure 4

CM-TNF-α upregulates the expressions of p-AKT and p-ERK of HLECs. C33A cells were stimulated with 10 ng/ml TNF-α for 48 h, and the CM was collected. Next, HLECs were cultured in CM with or without MAZ51 treatment. (a–c) The levels of AKT, p-AKT, ERK, and p-ERK of HLECs were measured by western blot. compared with CM group; ^## compared with CM-TNF-α group, .

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