Tumor Necrosis Factor-α Promotes the Tumorigenesis, Lymphangiogenesis, and Lymphatic Metastasis in Cervical Cancer via Activating VEGFC-Mediated AKT and ERK Pathways

Figure 6

TNF-α upregulates p-AKT and p-ERK expression in tumor tissues via mediating VEGFC signaling in vivo. (a) The level of VEGFC in the plasma was measured by ELISA. (b–d) The levels of AKT, p-AKT, ERK, and p-ERK in tumor tissue were measured by western blot. (e–g) The levels of VEGFC, D2-40, and VEGFR were detected with RT-qPCR. compared with control group; ^## compared with TNF-α treated group, .

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