Mediators of Inflammation

Research Article

Association between the Systemic Immune-Inflammation Index and Thyroid Function in U.S. Adults

Table 6

Association between lnSII and thyroid function after subgroup analysis by UIC.


Outcomes	<100 µg/L	≥100, <300 µg/L	≥300 µg/L	p for interaction
Outcomes	β (95% CI), p-value			p for interaction

FT3	−0.0343 (−0.0771, 0.0084)	−0.1125 (−0.1463, −0.0788)	−0.0412 (−0.0940, 0.0115)	0.007
TT4	0.1087 (−0.0200, 0.2373)	0.1737 (0.0721, 0.2753)	0.1016 (−0.0571, 0.2603)	0.639
FT3/FT4	−0.0801 (−0.1738, 0.0136)	−0.1481 (−0.2221, −0.0741)	−0.0796 (−0.1952, 0.0360)	0.428
TG	−0.6181 (−3.9921, 2.7558)	2.9681 (0.3038, 5.6324)	0.5213 (−3.6415, 4.6840)	0.229

Note: FT3, free triiodothyronine; FT4, free thyroxine; TT3, total triiodothyronine; TT4, total thyroxine; TG, thyroglobulin; and TGAb, thyroglobulin antibodies. , , . Bold value signifies the statistically significant variables clearly distinguishable from those that are not.