Key Roles of p53 Signaling Pathway-Related Factors GADD45B and SERPINE1 in the Occurrence and Development of Gastric Cancer

Figure 4

Correlation between 27 candidate genes in the p53 signaling pathway and prognosis in patients with GC analyzed by Lasso and multivariate cox regression. (a) In the figure, the name of the DEG is on the left, and the p-value is in the middle. The risk rate distribution of the genes is shown on the right side, where the left part indicates low risk and the right part indicates high risk. The HR indicates the risk rate; the risk rate greater than 1 indicates high risk, and less than 1 indicates low risk. (b) The abscissa represents the log (λ) value, the ordinate represents the coefficients value, the colored lines represent the genes used for the calculation, and the upper horizontal axis represents the number of genes. (c) The abscissa represents log (λ) value, and the ordinate represents partial likelihood deviance. The upper part is the corresponding log (λ) value, which can be used to calculate the number of genes retained. The dotted line shows partial likelihood deviance, the corresponding log (λ) value, and the number of genes retained in the optimal condition.

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