Research Article

Prognosis and Novel Drug Targets for Key lncRNAs of Epigenetic Modification in Colorectal Cancer

Table 1

The clinical characteristics of the different sets.

CovariatesTypeTotal setTraining setTesting set value

Age≤65227 (45.13%)161 (45.35%)66 (44.59%)0.9543
>65276 (54.87%)194 (54.65%)82 (55.41%)

GenderFemale225 (44.73%)157 (44.23%)68 (45.95%)0.7985
Male278 (55.27%)198 (55.77%)80 (54.05%)

RaceAsian9 (1.79%)6 (1.69%)3 (2.03%)0.9398
Black or African American246 (48.91%)175 (49.3%)71 (47.97%)
White248 (49.3%)174 (49.01%)74 (50%)

RadiationNo466 (92.64%)329 (92.68%)137 (92.57%)1
Yes37 (7.36%)26 (7.32%)11 (7.43%)

Pharmaceutical therapyNo301 (59.84%)212 (59.72%)89 (60.14%)1
Yes202 (40.16%)143 (40.28%)59 (39.86%)

Pathological stageStage I91 (18.09%)61 (17.18%)30 (20.27%)0.7053
Stage II180 (35.79%)129 (36.34%)51 (34.46%)
Stage III155 (30.82%)113 (31.83%)42 (28.38%)
Stage IV77 (15.31%)52 (14.65%)25 (16.89%)

Stage TT117 (3.38%)12 (3.38%)5 (3.38%)0.0901
T292 (18.29%)60 (16.9%)32 (21.62%)
T3343 (68.19%)253 (71.27%)90 (60.81%)
T450 (9.94%)30 (8.45%)20 (13.51%)
Tis1 (0.2%)0 (0%)1 (0.68%)

Stage MM0377 (74.95%)267 (75.21%)110 (74.32%)0.7588
M177 (15.31%)52 (14.65%)25 (16.89%)
Mx49 (9.74%)36 (10.14%)13 (8.78%)

Stage NN0283 (56.26%)200 (56.34%)83 (56.08%)0.7087
N1126 (25.05%)86 (24.23%)40 (27.03%)
N292 (18.29%)67 (18.87%)25 (16.89%)
Nx2 (0.4%)2 (0.56%)0 (0%)

StatusAlive403 (80.12%)284 (80%)119 (80.41%)1
Dead100 (19.88%)71 (20%)29 (19.59%)

No: the patient have not receive the treatment; Tis: carcinoma in situ; Mx: unknown M stage; Nx: unknown N stage.