The Role of Silymarin in Mitigating Inflammation and Cognitive Impairment Induced by Ovariectomy in Wistar Rats

Figure 4

Silymarin inhibits the expression of IL-1β, TNF-α, and IL-6 in the hippocampus after menopause. The mRNA expression levels of IL-1β (a), TNF-α (b), and IL-6 (c) were evaluated by qRT-PCR in samples of hippocampus tissue from five groups of rats. The experiments were conducted in triplicates, and the results are illustrated as the mean ± SD (n = 6 in each group). ( ; ; ) indicated statistical significance compared to the control group. (^#; ^##; ^###; ^####) indicated statistical significance compared to the sham group.

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