Integrative Analysis of Clinical and Bioinformatics Databases to Reveal the Role of Peripheral Innate Immunity in Kawasaki Disease

Figure 6

Cluster analysis of myeloid cells in KD from the GSE15245 dataset. (a) Cell types identified in myeloid cells using UMAP. (b) Violin plot depicts distributions of cell-type marker genes in monocytes and LILRA4 + pCD. (c) Volcano plot of DEGs in monocytes from KD patients. Upregulated genes are in red and downregulated genes are in blue. (d) Gene set variation analysis (GSVA) of significant hallmarks in monocytes, showing that DEGs are mainly involved in the regulation of immune response and TNFA signaling via NFKB.

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