circRNA_17725 Promotes Macrophage Polarization towards M2 by Targeting FAM46C to Alleviate Arthritis

Figure 9

circRNA_17725 promoted M2 polarization in CIA mice. (a) Flow cytometry: CD14⁺CD163⁺ cells and CD14⁺CD11c⁺ cells infiltration in spleens from CIA mice (, , and ; 6 mice/group, ). (b) Real-time PCR: CD11c, CD163, and FAM46C mRNA expressions in spleen mononuclear cells of CIA mice (, , and ; 6 mice/group, ). (c) ELISA: decreased TNF-α and IL-1β in the plasm from Lv-circRNA-transfected macrophage-treated CIA mice (, ; 6 mice/group, ).

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