Fibrinogen Is Associated with Prognosis of Critically Ill Patients with Sepsis: A Study Based on Cox Regression and Propensity Score Matching

Table 5

Aggregation of Cox regression model.

Model	Low level (<150 mg/dL)		High level (>400 mg/dL)
	HR (95% CI)	value	HR (95% CI)	value
Unadjusted	1.66 (1.42, 1.93)	<0.001	0.60 (0.53, 0.68)	<0.001
Model 1	1.79 (1.54, 2.09)	<0.001	0.59 (0.53, 0.67)	<0.001
Model 2	1.50 (1.28, 1.76	<0.001	0.64 (0.56, 0.72)	<0.001
Model 3	1.22 (1.03, 1.44)	0.022	0.66 (0.59, 0.75)	<0.001

The reference group was the normal fibrinogen group (150-400 mg/dL). Model 1 adjusted for age and gender. Model 2 adjusted for model 1 covariates+AKI, AMI, HF, liver cirrhosis, hypertension, COPD, CKD, AF, cerebral infarction, cerebral hemorrhage, thrombosis, and acute respiratory failure. Model 3 adjusts for model 2+WBC, Scr, hemoglobin, albumin, platelet, blood potassium, sodium, lactate, total bilirubin, glucose, prothrombin time (PT), and partial thromboplastin time (PTT), use of ventilation and RRT.