AdipoRon Engages Microglia to Antinociception through the AdipoR1/AMPK Pathway in SNI Mice

<div>AdipoRon regulated the AdipoR1/AMPK pathway in the ipsilateral spinal cord of SNI mice. (a) Representative fluorescence images of ipsilateral SDH showing double staining for AdipoR1 (red) and Iba-1 (green), GFAP (green), and NeuN (green), respectively. Scale bar: 100 <i>μ</i>M. (b–e) Representative Western Blots and quantification of AdipoR1, AMPK, and p-AMPK in the ipsilateral spinal cord of Sham, SNI, SNI+Vehicle, and SNI+AdipoRon on day 7 after surgery. 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27V0H384Z"></path></g></svg> vs. SNI+Vehicle-Ipsi.</div>

Mediators of Inflammation

fig3

Figure 3

Figure 3: AdipoRon Engages Microglia to Antinociception through the AdipoR1/AMPK Pathway in SNI Mice 