AdipoRon Engages Microglia to Antinociception through the AdipoR1/AMPK Pathway in SNI Mice

<div>Schematic illustration of the analgesic effect of AdipoRon. AdipoRon reduced M1-type microglia through the AdipoR1/AMPK pathway to inhibit TNF-<i>α</i> expression and improve mechanical nociception. The red arrows represent the pathological process, and the blue arrows represent the AdipoRon effect.</div>

Mediators of Inflammation

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Figure 6

Figure 6: AdipoRon Engages Microglia to Antinociception through the AdipoR1/AMPK Pathway in SNI Mice 